Whitepapers I Devyser

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Clinical significance of fetal-hemoglobin modifiers in β-thalassemia and sickle cell disease

This whitepaper provides an evidence-based overview of HbF genetic modifiers, their biological mechanisms, their clinical relevance, and how they should currently be interpreted in practice

Which is the best approach for CFTR diagnosis: Targeted NGS or whole exome sequencing?

This whitepaper explores the analytical and operational factors behind choosing targeted NGS for CFTR diagnosis.

Understanding HLA loss: A crucial component of post-transplant monitoring

This whitepaper discusses the importance of HLA loss monitoring in HSCT

Modernizing genetic testing for cystic fibrosis

This e-book addresses the importance of screening and Future-proofing CFTR testing with NGS

Devyser RHD Single-exon: High performance without complexity

This infographic details a modern approach to targeted, ethical, and efficient RhD management.

Challenges in laboratory detection of the α3.7 and α4.2 deletion in thalassemia

This whitepaper explores the diagnostic challenges posed by the α3.7 and α4.2 deletions in alpha thalassemia testing and the opportunities to overcome the limitations of traditional methods.

5reasons to choose Devyser Thalassemia

This infographic details how next-generation sequencing (NGS) can be used to help provide fast and accurate thalassemia diagnosis.

Advancing kidney transplant outcomes through dual-donor cfDNA monitoring

This whitepaper details how dd-cfDNA monitoring represents a significant advancement in the field of kidney transplantation.

Enabling the Early Detection and Targeted Intervention of Patients at Risk of Hereditary Cancer Syndromes

This report details how integrating genetic testing into cancer risk assessment and management has ushered in a new era of precision medicine

Have you future-proofed your cystic fibrosis testing?

This infographic details how next-generation sequencing (NGS) can be used to help overcome the challenges and provide fast and accurate cystic fibrosis testing

Meeting modern demands: How NGS can help overcome thalassemia testing challenges

This whitepaper details how next-generation sequencing (NGS) can be used to help overcome these challenges and provide fast and accurate thalassemia diagnosis.

Fetal RHD screening in clinical routine

Fetal RHD status can be determined with non-invasive prenatal testing, allowing administration of antenatal.

Five reasons to choose Devyser RHD

Learn about the 5 important reasons on why one should choose Devyser RHD, an assay that has been used to analyze many expectant mothers and helped them receive truly personalized care

Decoding Lynch Syndrome: The Clinical Imperative for Improved Genetic Testing

This whitepaper discusses the importance of genetic testing for Lynch syndrome, exploring the clinical impact of successful and unsuccessful Lynch syndrome testing, and the potential of emerging technologies to improve patient outcomes.

Detecting technically challenging PMS2 variants with NGS: Current techniques and future perspectives

In this whitepaper, we will discuss the importance, challenges, and techniques for detecting PMS2 variants and the implications for individuals with Lynch syndrome.

Improving Survival Rates for Patients Undergoing HSCT and the Role of NGS Testing

This report discusses the potential for modern NGS-based methods to improve the management of patients after HSCT.

Five IVDR challenges: What impact does IVDR have on your laboratory?

This whitepaper provides valuable insights into the key challenges and implications of IVDR compliance.

A simple NGS method for detection of sequence variants causing alpha and beta thalassemia

One oligo-mix to detect virtually all known variants for α- and β-thalassemia.

Overcoming limitations in the detection of mixed chimerism

This paper highlights the importance of chimerism as a diagnostic tool for clinicians treating transplanted patients.

Introduction to QF-PCR

A straightforward overview for laboratory professionals on how to operate a high-quality QF-PCR service — from basic set up to best.

Familial hypercholesterolemia: Genetic diagnosis and cascade testing using NGS

At present, FH is greatly underdiagnosed, and most cases are not discovered.

The role of chimerism monitoring following HSCT

Today HSCT is still the only curative treatment for patients with malignant or non-malignant hematological diseases.

QF-PCR and maternal cell contamination

This paper offers solid advice for laboratory professionals on using a QF-PCR-based approach to identify maternal cell contamination in uncultured AF and CV samples.

NGS: Changing the game in CFTR analysis

Many testing strategies have been developed in laboratories across the world.

QF-PCR in pregnancy loss analysis

This paper provides insights for laboratory professionals on the advantages of using extended QF-PCR in the genetic analysis of pregnancy loss samples.

NGS: Full gene sequencing of BRCA1 and BRCA2

With the increasing use of NGS, the number of detected variants in BRCA1 and BRCA2 are increasing.

Detecting mosaicism with QF-PCR

This paper provides straightforward advice for laboratory professionals on how to use QF-PCR to identify mosaicism in prenatal diagnostics.

CING of Cyprus transforms thalassemia testing with NGS

Dr. Papasavva describes her laboratory’s journey from traditional thalassemia testing to a state-of-the-art NGS technology and the difference this has made in their daily work.

A new NGS-based method for Chimerism monitoring

New, highly sensitive and precise methods for mixed chimerism analytics are transforming post-transplant monitoring, enabling earlier detection and treatment to save the lives of transplanted.

Guide to implementing NGS - simpler, faster, better

This guide addresses frequently asked questions and highlights key factors to consider when adding a new NGS test to your offering.