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Devyser HLA Loss

High-precision detection

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What is Devyser HLA Loss?

Devyser HLA Loss sets a new standard for accurately detecting mismatched HLA deletions, providing researchers with highly sensitive insights into immune escape mechanisms in post-transplantation scenarios through a streamlined, next-generation sequencing (NGS) workflow. 

Devyser HLA Loss – Product features

Discover how Devyser HLA Loss can optimize your research.

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High sensitivity, robust detection 

With robust assay linearity and a detection threshold below 0.2%, Devyser HLA Loss enables highly reliable identification of HLA loss events, delivering precise insights into subtle immune escape events. 

Streamlined workflow 

Simplify your processes with a convenient single-tube workflow requiring less than 45 minutes hands-on time, complemented by intuitive Advyser HLA Loss software for clear and rapid interpretation of results within 24 hours.

Informative and flexible design 

Benefit from a carefully curated panel featuring 25 HLA-locus-specific and 5 quality control chromosome-specific indel markers, providing consistent, population-independent data across diverse research cohorts. Devyser HLA Loss is a solution designed for integration with Devyser Chimerism NGS workflow.  

Why choose Devyser HLA Loss? 

Comprehensive insights: Combine Devyser HLA Loss seamlessly with your existing Devyser Chimerism NGS assay and achieve a complete picture of post-transplant immune escape. 

High analytical performance LoB, LoD, and LoQ all established at <0.2% 

Expert support: Rely on Devyser's dedicated and knowledgeable customer support team to ensure smooth assay implementation and ongoing assistance. 


IM-2022-NGS_2

Learn how Devyser HLA Loss brings clarity to your investigations

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Request a demo and introduce precise, efficient HLA loss detection to your lab today.

Downloads

Instructions for use

Enter access code found in the lower right corner of the label on the kit box.

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Certificates

Download a specific Batch Release Certificate (BRC) below.

Guidelines and handbooks (1)

Handbook Devyser HLA Loss 7-A156 BA 01 (English)

914 kb pdf

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Product information (0)

Software settings (2)

IEM files: Index Plate LB-A v2020-11-03 (English)

zip

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LB-A LRM files v2023-11-01 (English)

zip

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Safety data sheets (1)

SDS Devyser NGS products 7-A428 (English)

486 kb pdf

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Data tables (0)

Enter access code found in the lower right corner of the label on the kit box.

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Product details

RUO

Devyser HLA Loss

A simple NGS solution for precise detection of HLA Loss.

 

8-A416-8-RUO

8-A416-24-RUO

Pack size: 8

Pack size: 24

Frequently asked questions (FAQs) about Devyser HLA Loss

How many samples can be processed in a single batch using this kit?

We offer flexible batch sizes (Pack size—8 tests, Pack size— 24 tests) in combination with high in-use stability, offering flexible testing for low and high-throughput laboratories.   

Is this assay offered as a service?

No, the current product is a kit and software for research use only.  

Is specialized bioinformatics expertise required for data analysis?

No. Advyser HLA Loss is a software designed for intuitive, user-friendly operation accessible to all researchers.

What sensitivity can I expect for detecting HLA loss?

Devyser HLA Loss reliably detects HLA deletions at thresholds below 0.2%.

How quickly can I obtain results wth the Devyser HLA Loss solution?

The complete assay workflow takes less than 45 minutes hands-on time, with results delivered within 24 hours.

Disclaimer: Devyser HLA Loss is for research use only (RUO). Not for use in diagnostic procedures.​