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Devyser AZF v2

Detailed analysis of Y-chromosome microdeletions in the AZFa, AZFb and AZFc regions.

AZF

Detect all markers needed for basic AZF deletion screening

Test tube icon

One tube per sample means no need for sample splitting

Conforms to EAA and EMQN best practice guidelines

Product information

Testing according to EAA and EMQN best practice guidelines

All STS markers and control sequences, recommended by the European Academy of Andrology (EAA) and the European Quality Monitoring Network Group (EMQN) for basic molecular diagnosis of Y-chromosomal microdeletions in the AZFa, AZFb and AZFc regions are included in the kit. If a suspected deletion is detected an extended AZF marker analysis should be done using the Devyser AZF Extension kit. The use of fluorescently labelled primers for all markers allows automated visualization and identification of the STS markers using a Genetic Analyzer. Thus, eliminating multiple PCR reactions, use of toxic chemicals associated with the use of EtBr stained Agarose gels, and the guesswork associated with fragment identification

AZF testing kits

Diagnostic testing using Devyser AZF v2 relies on PCR amplification of sequence-tagged sites (STS) in the AZFa, AZFb and AZFc regions on the Y-chromosome. Successful amplification of an STS marker indicates presence, whereas absence of PCR amplification is indicative of deletion.

‍Devyser AZF v2 – for basic deletion testing

Devyser AZF v2 allows detailed analysis of Y-chromosome microdeletions in the AZFa, AZFb and AZFc regions. Conforms to the EAA and EMQN best practice guidelines for basic molecular diagnosis of Y-chromosomal microdeletions. Combine with Devyser AZF Extension for a complete basic and extended workflow

Downloads

Instructions for use

Enter access code found in the lower right corner of the label on the kit box.

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Certificates

Download a specific Batch Release Certificate (BRC) below.

Guidelines and handbooks (8)

Data Analysis Using GeneMapper 2018-12-10 (English)

pdf

Best practice guidelines AZF - EAA-EMQN 2013 (English)

pdf

Handbook Devyser AZF v2 RUO & Devyser AZF Extension RUO EN 2019-09-24 (English)

pdf

Accessory Pack Devyser AZF v2 version 2024-10 (English)

pdf

Addendum to handbook Devyser SeqStudio allele-specific products 7-B908 v2023-03-30 (English)

489 kb pdf

Addendum to handbook Devyser VeritiPro allele-specific products 7-B906 v2023-03-31 (English)

82 kb pdf

Addendum to Handbook 560 SIZER ORANGE Correction storage requirements 7-B917 v2024-09-13 (English)

106 kb pdf

Addendum to Handbook Dev-5 Dye Set MultiCap Correction storage requirements 7-B916 v2024-09-13 (English)

121 kb pdf

Product information (2)

Flyer - Devyser AZFv2 and AZF Extension (English)

pdf

IT Flyer - Devyser AZFv2 and AZF Extension (Italian)

pdf

Software settings (7)

Fragment Analysis Using ABI PRISM 310_2020-06-15 (English)

pdf

Fragment Analysis Using ABI 3730 & 3730xL 2020-06-15 (English)

pdf

Fragment Analysis Using ABI 3130 & 3130xL 2020-06-15 (English)

pdf

Fragment Analysis Using ABI 3500 & 3500xL 2020-06-15, c2021-01-19 (English)

pdf

GeneMapper Settings - Devyser AZF v2 & AZF Extension_GM4-5_2018-01-10 (English)

zip

Fragment analysis using SeqStudio v2023-02-13 (English)

pdf

Devyser Seqstudio Settings v.2022-12-29 (English)

4 kb

Safety data sheets (1)

SDS Devyser FA products 7-A429 v2024-01-10 (English)

569 kb pdf

Data tables (0)

Enter access code found in the lower right corner of the label on the kit box.

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Product details

CE-IVD

Devyser AZF v2

Chromosome Y microdeletion detection: AZFa: sY86, sY84 AZFb: sY127, sY134 AZFc: sY255, sY254 Controls: ZFY/ZFX, sY14 (SRY)

8-A019.2

Pack size: 25

RUO

Devyser AZF v2

Chromosome Y microdeletion detection: AZFa: sY86, sY84 AZFb: sY127, sY134 AZFc: sY255, sY254 Controls: ZFY/ZFX, sY14 (SRY)

8-A019.2-RUO

Pack size: 25

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Disclaimer: Products mentioned here are CE-IVD marked but not FDA-cleared. Availability in each country depends on local regulatory marketing authorization status. Please consult your local sales representative for details.