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One Lambda Devyser Chimerism NGS

Detect graft rejection and disease relapse in stem cell transplant patients at a very early stage with an advanced, single-tube chimerism testing solution. In collaboration with Thermo Fisher Scientific, this product is now available as One Lambda™ Devyser Chimerism NGS in the USA, Canada, and Europe.

Bubbling test tube

Quickly detect graft rejection, disease relapse and minimal residual disease by tight monitoring

45

Reduce hands-on time, below 45 minutes

0.05

High precision and sensitivity down to >0.05 percent

Sample. Analyze. Repeat.

Scientists working

One easy solution

The dd-cfDNA assay is a high-precision test solution for very early detection of graft rejection and disease relapse in stem cell transplant patients. It quickly detects microchimerism, graft rejection and any minimal residual disease. Requiring less than 45 minutes of hands-on time, the easy-to-use kit is designed for maximum lab efficiency and a fast and repeatable workflow, from patient sample to report. Screening samples are sequenced only once, saving time and increasing lab productivity. A single workflow for both screening and monitoring eliminates the need for sample-specific primers and patient-specific marker tracking. A single universal reagent mix for all patients also helps reduce reagent wastage and the need to keep multiple reagents in stock.

Highly sensitive and accurate

Results are highly accurate, with possible measurement of sensitivity to >0.05 percent. This is facilitated by combining the sensitive analysis of real-time PCR with precise measurements at high chimerism levels using STR fragment analysis. One tube per sample avoids any need for sample splitting. The single measurement method is independent of mixed chimerism levels, allowing true detection and monitoring of micro chimerism.

Dedicated data analysis

It is an end-to-end solution with dedicated software for fast, accurate result analysis. It reduces laboratory processing costs by ensuring targeted sequencing with high uniformity and by maximizing sample capacity on every next-generation sequence flow cell.

You are on this page because of an exclusive collaboration and distribution agreement between Devyser and Thermo Fisher Scientific.

Click for more information.

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Downloads

Instructions for use

Enter access code found in the lower right corner of the label on the kit box.

product card

Certificates

Download a specific Batch Release Certificate (BRC) below.

Guidelines and handbooks (2)

Handbook One Lambda Devyser Chimerism 7-A152 (English)

427 kb pdf

Handbook Devyser One Lambda Advyser Chimerism (English)

757 kb pdf

Product information (0)

Software settings (5)

Illumina double index (English)

pdf

IEM files: Index Plate LB-A v2020-11-03 (English)

zip

LRM files: Index Plate LB-A v2020-11-03 (English)

zip

Recipient (English)

Donor (English)

Safety data sheets (1)

SDS One Lambda Devyser Chimerism 7-A424 v2023-06-28 (English)

554 kb pdf

Data tables (0)

Enter access code found in the lower right corner of the label on the kit box.

product card

Product details

RUO

One Lambda Devyser Chimerism NGS

Screening and monitoring of mixed chimerism

8-A411-24

8-A411-48

Pack size: 24

Pack size: 48

CE-IVDR

One Lambda Devyser Chimerism NGS

Screening and monitoring of mixed chimerism

8-R107-24

8-R107-48

Pack size: 24

Pack size: 48