Detecting mosaicism with QF-PCR

Mosaicism in prenatal samples is a complex but important phenomenon. Optimal use of QF-PCR will identify most clinically significant cases of mosaicism, and also provide additional information regarding the origin of the abnormal cell line.

Authored by Dr. Kathy Mann, pioneer in prenatal QF-PCR analysis, it includes useful sections on: assay design, sample processing, limitations and much more..

• Significant benefits of the genotyping aspect of QF-PCR.
• Why the use of dissociated cells is now recommended as part of UK best practice.
• How optimal use of QF-PCR will identify most clinically significant cases of mosaicism and more.