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Devyser Chimerism NGS

Detect graft rejection and disease relapse in stem cell transplant patients at a very early stage with an advanced, single-protocol chimerism testing solution.

Bubbling test tube

Quickly detect graft rejection, disease relapse and minimal residual disease by tight monitoring

45

Reduce hands-on time, below 45 minutes

0.05

High precision and sensitivity down to >0.05 percent

Sample. Analyze. Repeat.

Scientists working

One easy solution

Devyser Chimerism NGS is a high-precision test solution for very early detection of graft rejection and disease relapse in stem cell transplant patients. It quickly detects microchimerism, graft rejection and any minimal residual disease. Requiring less than 45 minutes of hands-on time, the easy-to-use kit is designed for maximum lab efficiency and a fast and repeatable workflow, from patient sample to report. Screening samples are sequenced only once, saving time and increasing lab productivity. A single workflow for both screening and monitoring eliminates the need for sample-specific primers and patient-specific marker tracking. A single universal reagent mix for all patients also helps reduce reagent wastage and the need to keep multiple reagents in stock.

Highly sensitive and accurate

Results are highly accurate, with possible measurement of sensitivity to >0.05 percent. This is facilitated by combining the sensitive analysis of real-time PCR with precise measurements at high chimerism levels using STR fragment analysis. One tube per sample avoids any need for sample splitting. The single measurement method is independent of mixed chimerism levels, allowing true detection and monitoring of micro chimerism.

Dedicated data analysis

Devyser Chimerism is an end-to-end solution with dedicated software for fast, accurate result analysis. It reduces laboratory processing costs by ensuring targeted sequencing with high uniformity and by maximizing sample capacity on every next-generation sequence flow cell.

Downloads

Instructions for use

Enter access code found in the lower right corner of the label on the kit box.

product card

Certificates

Download a specific Batch Release Certificate (BRC) below.

Guidelines and handbooks (1)

Handbook Devyser Chimerism EN v2021-04-15 (English)

pdf

Product information (4)

PIB - Devyser Chimerism (English)

pdf

Flyer: Devyser Chimerism (Italian) (Italian)

pdf

Flyer: Devyser Chimerism (English) (English)

pdf

Performance Parameters of an NGS Product for Chimerism Monitoring (English)

pdf

Software settings (11)

Devyser Calculator 2020-01-20 (English)

pdf

MiSeq IEM Files (English)

zip

Illumina double index (English)

Guide ADVYSER Devyser Chimerism - Czech (Czech)

pdf

Guide ADVYSER Devyser Chimerism - English (English)

pdf

Recipient (English) (English)

Donor (English) (English)

LRM files: Index Plate LB-A v2020-11-03 (English)

zip

LRM files: v2020-05-26 (English)

zip

IEM files: Index Plate LB-A v2020-11-03 (English)

zip

Devyser Sequence Coverage Calculator for Chimerism (English)

pdf

Safety data sheets (5)

Devyser SDS 2 RUO EN (English)

pdf

Devyser SDS 1 CE-IVD EN (English)

pdf

Devyser SDS 2 RUO DE (German)

pdf

Devyser SDS 1 CE-IVD IT (Italian)

pdf

Devyser SDS 2 RUO IT (Italian)

pdf

Data tables (0)

Enter access code found in the lower right corner of the label on the kit box.

product card

Product details

CE-IVD

Devyser Chimerism NGS

Screening and monitoring of mixed chimerism

8-A107-24

8-A107-48

Pack size: 24

Pack size: 48

RUO

Devyser Chimerism NGS

Screening and monitoring of mixed chimerism

8-A405-24

8-A405-48

Pack size: 24

Pack size: 48

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Data analysis made easy

Fast and effective test data analysis is crucial to achieving accurate outcomes and efficient workflows.

Dedicated software in our products makes analyzing test results quick, easy and trouble-free. For users, this means a streamlined end-to-end process with unmatched reliability and transparency.

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