Expert Review 02
Detecting mosaicism with QF-PCR by Dr Kathy Mann
Mosaicism in prenatal samples is a complex but important phenomenon. Optimal use of QF-PCR will identify most clinically significant cases of mosaicism, and also provide additional information regarding the origin of the abnormal cell line.
Authored by Dr. Kathy Mann, pioneer in prenatal QF-PCR analysis, it includes useful sections on: assay design, sample processing, limitations and much more.
What you'll learn
Origin of mosaicism
Significant benefits of the genotyping aspect of QF-PCR
Why the use of dissociated cells is now recommended as part of UK best practice
How optimal use of QF-PCR will identify most clinically significant cases of mosaicism and more