Devyser BRCA1 and BRCA2 for NGS

Reduce hands-on time from days to minutes with Devyser’s single tube, next-generation sequencing (NGS) library prep kit for fast and complete characterisation of BRCA1 and BRCA2.

Discover the advantages of Devyser’s NGS workflow

  • Detect all mutations in BRCA1 and BRCA2
  • One tube per sample means no need for sample splitting
  • Reduce hands-on time from days to under 45 minutes
  • One kit for both germline and somatic mutations
  • Choice of several validated software options, including CNV analysis

NGS has never been easier

The Devyser BRCA kit is easy to implement and highly cost-effective, making it a good match for laboratories of any size. With ready-to-use reagents and a user-friendly workflow, it suites both manual and automated workflows. Devyser’s unique single-tube approach simplifies the workflow, reduces hands-on time and minimizes the risk of sample mix-up and contamination. 

The proprietary multiplex PCR primer chemistry provides full and uniform coverage of BRCA1 and BRCA2, covering all exons and exon/intron junctions. The kit uses overlapping primer design to ascertain superior INDEL coverage and downstream CNV analysis. The Devyser BRCA kit can be used to detect both germline and somatic mutations. 

Devyser BRCA-NGS

Analytical software options

Laboratories have a choice of fully validated analytical software solutions, locally deployed or cloud-based. We also support integration with other analytical software solutions.

About BRCA mutation testing

Early identification of germline BRCA mutations can help physicians make informed decisions on risk reduction strategies such as hormone replacement therapy, chemoprevention strategies and prophylactic surgery. Analysis of somatic mutations can help clinicians tailor targeted treatment for ovarian and breast cancer patients.

Devyser BRCA1 and BRCA2 for NGS

Reduce hands-on time from days to minutes with Devyser’s single tube, next-generation sequencing (NGS) library prep kit for fast and complete characterisation of BRCA1 and BRCA2.

Discover the advantages of Devyser’s NGS workflow

  • Detect all mutations in BRCA1 and BRCA2
  • One tube per sample means no need for sample splitting
  • Reduce hands-on time from days to under 45 minutes
  • One kit for both germline and somatic mutations
  • Choice of several validated software options, including CNV analysis

NGS has never been easier

The Devyser BRCA kit is easy to implement and highly cost-effective, making it a good match for laboratories of any size. With ready-to-use reagents and a user-friendly workflow, it suites both manual and automated workflows. Devyser’s unique single-tube approach simplifies the workflow, reduces hands-on time and minimizes the risk of sample mix-up and contamination. 

The proprietary multiplex PCR primer chemistry provides full and uniform coverage of BRCA1 and BRCA2, covering all exons and exon/intron junctions. The kit uses overlapping primer design to ascertain superior INDEL coverage and downstream CNV analysis. The Devyser BRCA kit can be used to detect both germline and somatic mutations. 

Devyser BRCA-NGS

Analytical software options

Laboratories have a choice of fully validated analytical software solutions, locally deployed or cloud-based. We also support integration with other analytical software solutions.

About BRCA mutation testing

Early identification of germline BRCA mutations can help physicians make informed decisions on risk reduction strategies such as hormone replacement therapy, chemoprevention strategies and prophylactic surgery. Analysis of somatic mutations can help clinicians tailor targeted treatment for ovarian and breast cancer patients.

  • Whitepapers
  • Downloads

IFU and software settings

Enter access code found in the lower right corner of the label on the kit box.

Certificates

Download a specific Batch Release Certificate (BRC) below by entering the BATCH/LOT number and then click on "Find".

Whitepapers

Whitepaper NGS GENE SEQUENCING BRCA1 & BRCA2

NGS: Full Gene Sequencing of BRCA1 and BRCA2

With the increasing use of NGS, the number of detected variants in BRCA1 and BRCA2 are increasing fast. As a consequence, the absolute numbers of Variants of Uncertain Significance (VUS) are also increasing. This paper describes current initiatives to classify and interpret VUS in BRCA1 and BRCA2, and how laboratories can contribute to these efforts and ultimately improve the counseling of tested patients.

Find out more about our BRCA NGS products or Contact Us.

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We are specialists when it comes to diagnostic kits for complex DNA testing within oncology, reproductive health and hereditary diseases. Our products are used to guide targeted cancer therapies, to enable rapid prenatal diagnostics, as well as in a wide array of genetic tests. Routine diagnostic laboratories in more than 50 countries worldwide use our products.