Devyser Compact

Devyser Compact: one single mix, 26 genetic markers

Devyser Compact enables rapid prenatal aneuploidy detection of chromosomes 13, 18, 21 and XY in a single PCR mix.

In addition to detecting Down, Edwards, Patau and Klinefelter syndromes, the Devyser Compact kit includes our patented technology for reliable diagnosis of Turner syndrome, using two dedicated X-chromosome counting markers. The CE-IVD certified Devyser Compact kit relies on quantitative, multiplex PCR amplification of 26 highly informative genetic markers in a single mix for rapid prenatal diagnosis of the most common autosomal and sex chromosome aneuploidies.

  • Efficient and sensitive detection of chromosomal aneuploidies and maternal cell contamination (MCC) in DNA samples prior to microarray analysis
  • No sample mix-up. One single tube per sample during PCR and detection reduces the risk of sample mix-up.
  • Quick and easy implementation. All reagents needed to perform QF-PCR are provided in a single kit.

Eliminate cell culture, increase analysis success rates and speed up your pregnancy loss aneuploidy analysis for chromosomes 13, 15, 16, 18, 21, 22 and XY using Devyser Extend.

Pregnancy loss analysis
Women who have undergone one or more spontaneous abortions caused by chromosomal abnormalities are at increased risk for chromosomal abnormalities in future pregnancies. Cytogenetic studies of miscarriages are highly recommended even in the case of the first pregnancy loss. Identification of the possible cause of fetal loss significantly reduces the long-term psychological distress associated with a miscarriage and enables improved genetic counselling in future pregnancies. The most frequently observed numerical chromosomal abnormalities involve chromosomes 13, 15, 16, 18, 21, 22 and X.

Conventional analysis
Conventional cytogenetic studies (karyotyping or FISH) are expensive and need a long period of time in order to obtain results. Moreover, they result in high rates of culture failure, misdiagnosis due to maternal contamination and cell overgrowth as well as insufficient quality of chromosome preparations. Cell culture may selectively yield normal karyotypes or selected abnormal karyotypes that survive in-vitro cell proliferation.

QF-PCR for pregnancy loss analysis
QF-PCR does not require cell culture, requires minute amounts of tissue material and allows the lab to obtain results within one working day. The Devyser Extend kit includes 42 genetic markers for aneuploidy analysis by QF-PCR of chromosomes 13, 15, 16, 18, 21, 22, X and Y. Two unique X-chromosome counting markers for reliable detection of Turner syndrome are also included in Devyser Extend.

The Devyser Resolution kits are QF-PCR kits intended for rapid prenatal aneuploidy analysis of individual chromosomes, including chromosomes 13, 18, 21 and XY. See product details for more information. 

Devyser Complete enables rapid prenatal 
aneuploidy detection of chromosomes 13, 18, 21 and XY using 33 genetic markers in two separate PCR mixesCross mix ID markers are included in both mixes to reduce the risk of sample mix-up. In addition to detecting Down, Edwards, Patau and Klinefelter syndromes, the Devyser Complete kit includes our patented technology for reliable diagnosis of Turner syndrome, using two dedicated X-chromosome counting markers. 

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Product details

CE-IVD Certified Kits

Name
Scope
Pack Size
Article Number
Devyser Compact v3
Aneuploidy determination of chromosomes 13, 18, 21, X and Y
25
8-A017.3-25
50
8-A017.3-50
100
8-A017.3-100
Devyser Extend v2
Aneuploidy determination of chromosomes 13, 15, 16, 18, 21, 22, X and Y
25
8-A015.2
100
8-A012.2-100
Devyser Extend M1 v2
Aneuploidy determination of chromosomes 15, 16 and 22
25
8-A015.2-M1
Devyser Resolution 13 v2
Aneuploidy determination of chromosome 13
25
8-A012.2-13
Devyser Resolution 18 v2
Aneuploidy determination of chromosome 18
25
8-A012.2-18
Devyser Resolution 21 v2
Aneuploidy determination of chromosome 21
25
8-A012.2-21
Devyser Resolution XY v2
Aneuploidy determination of chromosomes X and Y
25
8-A012.2-XY
Devyser Complete v2
Aneuploidy determination of chromosomes 13, 18, 21, X and Y
25
8-A011.2-25
50
8-A011.2-50
100
8-A011.2-100

Research Use Only Kits

Name
Scope
Pack Size
Article Number
Devyser Compact v3
Aneuploidy determination of chromosomes 13, 18, 21, X and Y
25
8-A017.3-25-RUO
50
8-A017.3-50-RUO
100
8-A017.3-100-RUO
Devyser Extend v2
Aneuploidy determination of chromosomes 13, 15, 16, 18, 21, 22, X and Y
25
8-A015.2-RUO
Devyser Extend M1 v2
Aneuploidy determination of chromosomes 15, 16 and 22
25
8-A015.2-M1RUO
Devyser Resolution 13 v2
Aneuploidy determination of chromosome 13
25
8-A012.2-13RUO
Devyser Resolution 18 v2
Aneuploidy determination of chromosome 18
25
8-A012.2-18RUO
Devyser Resolution 21 v2
Aneuploidy determination of chromosome 21
25
8-A012.2-21RUO
Devyser Resolution XY v2
Aneuploidy determination of chromosomes X and Y
25
8-A012.2-XYRUO
Devyser Complete v2
Aneuploidy determination of chromosomes 13, 18, 21, X and Y
25
8-A011.2-25-RUO
50
8-A011.2-50-RUO
100
8-A011.2-100-RUO

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We are specialists when it comes to diagnostic kits for complex DNA testing within oncology, reproductive health and hereditary diseases. Our products are used to guide targeted cancer therapies, to enable rapid prenatal diagnostics, as well as in a wide array of genetic tests. Routine diagnostic laboratories in more than 50 countries worldwide use our products.

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