Emily Carter

CRISPR-Cas9 presents new possibilities for Thalassemia treatment.

The autosomal recessive inherited blood disorder, b-thalassemia, is caused by reduced or absent synthesis of the beta chains of hemoglobin due to mutations within the HBB gene. The severity of the disease depends on the nature of the mutation and whether the mutations are present in heterozygous or homozygous form. Another autosomal recessive inherited hemoglobinopathy …

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Visit us at EFI 2019

Just two weeks to go until this years European Immunogenetics and Histocompatibility Conference in Lisbon, Portugal. Will you be attending? Keep an eye out for the poster presentation “Performance Paramaters of an NGS Product for Chimerism Monitoring” and visit the Devyser stand at booth 13 to find out more about our new product for the …

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On our way to IVDR Compliance

We are very happy to announce that TÜV SÜD has verified the update of our quality management system to the latest revision – ISO13485:2016! This is the first milestone in our compliance and transition from the previous IVD Directive (IVDD) to the newly adopted IVD Regulation (IVDR).

Devyser launches first NGS-based test for mixed chimerism

Swedish molecular diagnostics company Devyser, announced today at the 45th annual European Bone Marrow Transplantation (EBMT) meeting in Frankfurt, Germany, the release of a new NGS-based assay for ultrasensitive and precise measurement of mixed chimerism after Human Stem Cell Transplantation. At EBMT, Devyser presented data obtained with the new Devyser Chimerism assay generated in collaboration …

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Simplify Gene Transcript Selection Using MANE Transcripts

For many genes, choosing the most optimal transcript for a specific analysis is a complex task. This is due to two main factors. Firstly, the frequently large number of transcripts listed for a certain gene, and also because gene browsers are inconsistent in the definition of which transcripts are considered to be “default”. NCBI (RefSeq) …

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Clinical trials highlights the importance of correct CFTR mutation detection in cystic fibrosis patients

Cystic Fibrosis is one of the most common genetic disorders. The disease is caused by mutations within the cystic fibrosis transmembrane conductance regulator gene (CFTR) leading to gradually decreasing lung function in affected patients. Current treatment protocols include symptomatic treatments for cystic fibrosis and a CFTR potentiator (Ivacaftor), which increases CFTR channel opening at the …

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No Significant Reduction in Miscarriage Rates from NIPT Pre-Screening for Trisomy 21 as compared to invasive testing

A recent paper published by Malan et al in the Journal of the American Medical Association (JAMA) describes a clinical study conducted over two years looking into the potential for reducing risk of miscarriage when performing cell-free fetal DNA (cfDNA) testing, NIPT testing, as compared to invasive fetal testing procedures. It has been hypothesised that …

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Visit Us at ASHG 2018!

Devyser is excited to be attending this years ASHG event in San Diego, next week. As one of the major events in the American continent we look forward to attending some interesting presentations, and members of our staff will also be presenting two posters. Come and visit us in booth #945 and say hi, or …

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